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Epigenetic modifications and human pathologies: cancer and CVD

11 Nov 2010

Abstract excerpt

Epigenetic changes are inherited alterations in DNA that affect gene expression and function without altering the DNA sequence. DNA methylation is one epigenetic process implicated in human disease that is influenced by diet. DNA methylation involves addition of a 1-C moiety to cytosine groups in DNA. Methylated genes are not transcribed or are transcribed at a reduced rate. Global under-methylation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21067630
DOI: 10.1017/s0029665110003952

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