Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Malignant melanoma and Wiedemann-Beckwith syndrome in childhood.

Klinische Padiatrie - 1 Nov 2010

Livingstone E, Caliebe A, Egberts F, Proksch E, Buiting K, Schubert C, Claviez A, Siebert R, Hauschild A

Abstract excerpt

Patients with Wiedemann-Beckwith syndrome (WBS, MIM 130650), a congenital overgrowth syndrome, have a known increased tumor risk especially for embryonic tumors. WBS belongs to the "imprinting" syndromes caused by overexpression of IGF2 and/or loss of CDKN1C on chromosome 11p15.5. A 13-year-old boy with WBS developed a spitzoid malignant melanoma (Clark level V, Breslow index 4.8 mm) on the right cheek. Genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Beckwith-Wiedemann Syndrome
Share to Chromosomes, Human, Pair 11

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Genomic Imprinting

Share to Melanoma

Share to RNA, Long Noncoding

Share to RNA, Untranslated

Share to Skin Neoplasms

Source

Identifiers

PMID: 21058226
DOI: 10.1055/s-0030-1267152

Genes

IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Malignant melanoma and Wiedemann-Beckwith syndrome in childhood.PMID 21058226Read ↗

Molecular genetics of Wiedemann-Beckwith syndromeSemantic proximity Read ↗

Wiedman-Beckwith syndrome, tumorigenesis and imprinting.Semantic proximity Read ↗

Clinical Spectrum and Tumour Risk Analysis in Patients with Beckwith-Wiedemann Syndrome Due to CDKN1C Pathogenic VariantsSemantic proximity Read ↗

Beckwith–Wiedemann syndromeSemantic proximity Read ↗

Expanded phenotype and cancer risk in patients with Beckwith-Wiedemann spectrum caused by CDKN1C variants.Semantic proximity Read ↗

(Epi)genotype–phenotype correlations in Beckwith–Wiedemann syndrome: a paradigm for genomic medicineSemantic proximity Read ↗

Epigenotype, genotype, and phenotype analysis of patients in Taiwan with Beckwith-Wiedemann syndrome.Semantic proximity Read ↗

Phenotype, cancer risk, and surveillance in Beckwith-Wiedemann syndrome depending on molecular genetic subgroups.Semantic proximity Read ↗

Beckwith-Wiedemann syndrome.Semantic proximity Read ↗

Mutations of the Imprinted CDKN1C Gene as a Cause of the Overgrowth Beckwith-Wiedemann Syndrome: Clinical Spectrum and Functional Characterization.Semantic proximity Read ↗

Tumor risk in Beckwith–Wiedemann syndrome: A review and meta‐analysisSemantic proximity Read ↗

Genetic diseases associated with an increased risk of skin cancer development in childhood.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.