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Article

Expanded CTG repeat demarcates a boundary for abnormal CpG methylation in myotonic dystrophy patient tissues.

Human molecular genetics - 1 Jan 2011

López Castel Arturo, Nakamori Masayuki, Tomé Stephanie, Chitayat David, Gourdon Geneviève, Thornton Charles A, Pearson Christopher E

Abstract excerpt

Myotonic dystrophy (DM1) affects multiple organs, shows age-dependent progression and is caused by CTG expansions at the DM1 locus. We determined the DM1 CpG methylation profile and CTG length in tissues from DM1 foetuses, DM1 adults, non-affected individuals and transgenic DM1 mice. Analysis inc...

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Source

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Identifiers

PMID: 21044947
DOI: 10.1093/hmg/ddq427
PMCID: PMC3000673

Genes

CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21044947-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Expanded CTG repeat demarcates a boundary for abnormal CpG methylation in myotonic dystrophy patient tissues.PMID 21044947Read ↗

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