Article
AbaA and WetA govern distinct stages of Aspergillus fumigatus development.
Microbiology (Reading, England) - 1 Feb 2011
Tao Li, Yu Jae-Hyuk
Abstract excerpt
The opportunistic human pathogen Aspergillus fumigatus produces a massive number of asexual spores (conidia) as the primary means of dispersal, survival, genome protection and infection of hosts. In this report, we investigate the functions of two developmental regulators, AfuAbaA and AfuWetA, in A. fumigatus. The AfuabaA gene is predicted to encode an ATTS/TEA DNA-binding domain protein and is activated by...
Topics
- Aspergillus fumigatus
- Cell Death
- Cell Wall
- DNA, Fungal
- DNA-Binding Proteins
- Fungal Proteins
- Gene Deletion
- Gene Expression Regulation, Fungal
- Microbial Viability
- Mutation
- Open Reading Frames
- Spores, Fungal
- Transcription Factors
- Trehalose
