Article
CD36 deficiency predisposing young children to fasting hypoglycemia.
Metabolism: clinical and experimental - 1 Jun 2011
Nagasaka Hironori, Yorifuji Tohru, Takatani Tomozumi, Okano Yoshiyuki, Tsukahara Hirokazu, Yanai Hidekatsu, Hirano Ken-ichi, Hui Shu-Ping, Hirayama Satoshi, Ito Tetsuya, Chiba Hitoshi, Miida Takashi
Abstract excerpt
Fatty acid (FA) β-oxidation defects cause hypoglycemia. Our aim was to determine if CD36--a membrane transporter for long-chain FAs--deficiency predisposes children to hypoglycemia. After overnight fasting, we measured parameters for carbohydrate and FA metabolisms at 12-, 14-, and 16-hour fasting points in 51 preschool children with histories of episodic hypoglycemia and 49 age-matched healthy controls....
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