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Article

CXCR7 Protein Is Not Expressed on Human or Mouse Leukocytes

2 Oct 2010

Abstract excerpt

Since the discovery that CXCR7 binds to CXCL12/SDF-1α, the role of CXCR7 in CXCL12-mediated biological processes has been under intensive scrutiny. However, there is no consensus in the literature on the expression of CXCR7 protein by peripheral blood cells. In this study we analyzed human and mouse leukocytes and erythrocytes for CXCR7 protein expression, using a competitive CXCL12 binding assay as well as by...

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PMID: 20889540
DOI: 10.4049/jimmunol.1001660

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