Article
[The role of polymorphic variants of gene of inducible NO-synthase NOS2 in brain infarction in patients with acute ischemic stroke].
Molekuliarnaia genetika, mikrobiologiia i virusologiia - 1 Jan 2010
Tupitsyna T V, Bondarenko E A, Botsina A Iu, Shetova I M, Limborskaia S A, Skvortsova V I, Slominskiĭ P A
Abstract excerpt
Cerebrovascular diseases including stroke are an important problem of public health. Stroke development depends on external factors and individual genetic specificity of patient. Excessive NO production by inducible NO-synthase (iNOS) damages brain tissue at various stages of the disease. The goal of this work was to study the role of 4 polymorphic variants of gene of inducible NO-synthase iNOS (-2447C/G,...
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