Article
[Genome-wide scanning in the study of risk for cerebral stroke].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2009
Skvortsova V I, Limborskaia S A, Shetova I M, Slominskiĭ P A, Botsina A Iu, Shamalov N A, Tupitsyna T V
Abstract excerpt
The role of genetic predisposition to the formation of most multifactorial diseases, including stroke, was demonstrated in a number of investigations. To determine the individual genetic risk of a polygenic disease, the candidate gene approach is used most often. It is based on the analysis of polymorphic variants of certain genes taking into consideration the function of their protein product. But this approach...
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