Article
[Polymorphic markers TCF7L2 rs12255372 and SLC30A8 rs13266634 confer susceptibility to type 2 diabetes in a Russian population].
Genetika - 1 Aug 2010
Potapov V A, Shamkhalova M N, Smetanina S A, Bel'chikova L N, Suplotova L A, Shestakova M V, Nosikov V V
Abstract excerpt
Genes 7CF7L2 and SLC30A8, encoding transcription factor-4 and transmembrane zinc transporter-8, respectively, play an important role in the regulation of development, proliferation, and pancreatic beta cell function. In the present study we examined polymorphic markers of genes rs12255372 [NT_03359.12:g33557428G --> T] of 7CF7L2 gene and rs13266634 [NP_776250.2:p.R325W] of SLC30A8 in groups of Russians with type...
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