Article
Genetic heterogeneity of Oguchi's disease.
Indian journal of ophthalmology - 1 Jan 2000
Singh J R
Abstract excerpt
An analysis of the cases reported in Punjab, India, indicates the presence of genetic heterogeneity of Oguchi's disease, for which autosomal recessive inheritance has been documented earlier. The autosomal dominant inheritance pattern of this disease is associated with incomplete penetrance and a distinct sex bias towards females. This recognition is important for genetic counselling.
Topics
- Adolescent
- Adult
- Child
- Child, Preschool
- Chromosome Aberrations
- Chromosome Disorders
- Female
- Genetic Variation
- Humans
- Male
- Night Blindness
- Pedigree