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Article

Deletion and duplication of 15q24: molecular mechanisms and potential modification by additional copy number variants.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Sept 2010

El-Hattab Ayman W, Zhang Feng, Maxim Rolanda, Christensen Katherine M, Ward Jewell C, Hines-Dowell Stacy, Scaglia Fernando, Lupski James R, Cheung Sau Wai

Abstract excerpt

PURPOSE: To investigate the potential influence of additional copy number variants in patients with 15q24 rearrangements and the possible underlying mechanisms for these rearrangements. METHODS: Oligonucleotide-based chromosomal microarray analyses were performed, and the results were subsequently confirmed by fluorescence in situ hybridization analyses. Long-range polymerase chain reaction amplification and DNA...

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Source

Identifiers

PMID: 20860070
DOI: 10.1097/GIM.0b013e3181eb9b4a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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