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Variable and often severe phenotypic expression in patients with the α-thalassemic variant Hb Agrinio [α29(B10)Leu→Pro (α2)].

Hemoglobin - 1 Jan 2010

Traeger-Synodinos Joanne, Douna Varvara, Papassotiriou Ioannis, Stamoulakatou Alexandra, Ladis Vasilis, Siahanidou Tania, Fylaktou Irine, Kanavakis Emmanuel

Abstract excerpt

Hb Agrinio [α29(B10)Leu→Pro] is a highly unstable variant, classified as a nondeletional α-thalassemia (α-thal) mutation. To date it has only been described in individuals of Greek and Cypriot origin. Evaluation of the phenotypic presentation of 12 Hb Agrinio homozygotes or compound heterozygotes, diagnosed in a single center in Greece during a 15-year period, found a wide clinical expression, ranging from...

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Identifiers

PMID: 20854116
DOI: 10.3109/03630269.2010.509224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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