Article
Genetics and vaccine efficacy: host genetic variation affecting Marek's disease vaccine efficacy in White Leghorn chickens.
Poultry science - 1 Oct 2010
Chang S, Dunn J R, Heidari M, Lee L F, Song J, Ernst C W, Ding Z, Bacon L D, Zhang H
Abstract excerpt
Marek's disease (MD) is a T-cell lymphoma disease of domestic chickens induced by MD virus (MDV), a naturally oncogenic and highly contagious cell-associated α-herpesvirus. Earlier reports have shown that the MHC haplotype as well as non-MHC genes are responsible for genetic resistance to MD. The MHC was also shown to affect efficiency of vaccine response. Using specific-pathogen-free chickens from a series of 19...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.