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Article

New Delhi Metallo-beta lactamase (NDM-1) in Enterobacteriaceae: treatment options with carbapenems compromised.

The Journal of the Association of Physicians of India - 1 Mar 2010

Deshpande Payal, Rodrigues Camilla, Shetty Anjali, Kapadia Farhad, Hedge Ashit, Soman Rajeev

Abstract excerpt

BACKGROUND: Carbapenems are among the few useful antibiotics against multidrug resistant gram negative bacteria particularly those with extended spectrum beta lactamase. However resistance to carbapenems occurs and is mediated by mechanisms like loss of outer membrane proteins and production of beta lactamase that is capable of hydrolyzing carbapenems. An alert issued in the UK in 2009 warned of an increasing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20848811

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