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Article

Silver-Russell patients showing a broad range of ICR1 and ICR2 hypomethylation in different tissues.

Clinical genetics - 1 Jul 2011

Begemann M, Spengler S, Kanber D, Haake A, Baudis M, Leisten I, Binder G, Markus S, Rupprecht T, Segerer H, Fricke-Otto S, Mühlenberg R, Siebert R, Buiting K, Eggermann T

Abstract excerpt

In all known congenital imprinting disorders an association with aberrant methylation or mutations at specific loci was well established. However, several patients with transient neonatal diabetes mellitus (TNDM), Silver-Russell syndrome (SRS) and Beckwith-Wiedemann syndrome (BWS) exhibiting multilocus hypomethylation (MLH) have meanwhile been described. Whereas TNDM patients with MLH show clinical symptoms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20738330
DOI: 10.1111/j.1399-0004.2010.01514.x

Genes

DNMT1
MBD3
ZFP57

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Silver-Russell patients showing a broad range of ICR1 and ICR2 hypomethylation in different tissues.PMID 20738330Read ↗

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