Article
Low frequency of common LRRK2 mutations in Mexican patients with Parkinson's disease.
Neuroscience letters - 19 Nov 2010
Yescas Petra, López Marisol, Monroy Nancy, Boll Marie-Catherine, Rodríguez-Violante Mayela, Rodríguez Ulises, Ochoa Adriana, Alonso María Elisa
Abstract excerpt
Mutations in leucine-rich repeat kinase 2 gene (LRRK2) account for as much as 5-6% of familial Parkinson's disease (PD) and 1-2% of sporadic PD. These mutations represent the most frequent cause of autosomal dominant PD, particularly in certain ethnic groups. In this first report concerning LRRK2 mutations in Mexican-mestizos, we screened 319 consecutive PD patients (186 males; 133 females; mean age at onset:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.