Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Double heterozygous mutations involving both HNF1A/MODY3 and HNF4A/MODY1 genes: a case report.

Diabetes care - 1 Nov 2010

Forlani Gabriele, Zucchini Stefano, Di Rocco Antonio, Di Luzio Raffaella, Scipione Mirella, Marasco Elena, Romeo Giovanni, Marchesini Giulio, Mantovani Vilma

Abstract excerpt

OBJECTIVE: We describe a maturity-onset diabetes of the young (MODY) case with mutations involving both HNF4A and HNF1A genes. RESEARCH DESIGN AND METHODS: A male patient was diagnosed with diabetes at age 17; the metabolic control rapidly worsened to insulin requirement. At that time no relatives were known to be affected by diabetes, which was diagnosed years later in both the parents (father at age 50 years,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Hepatocyte Nuclear Factor 1-alpha

Share to Hepatocyte Nuclear Factor 4

Share to Mutation

Share to Pedigree

Source

Open in PubMed Open full text

Identifiers

PMID: 20705777
DOI: 10.2337/dc10-0561
PMCID: PMC2963490

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Double heterozygous mutations involving both HNF1A/MODY3 and HNF4A/MODY1 genes: a case report.PMID 20705777Read ↗

Novel insights into genetics and clinics of the HNF1A-MODYSemantic proximity Read ↗

Three novel mutations in MODY and its phenotype in three different Czech families.Semantic proximity Read ↗

Divergent phenotypes in siblings with identical novel mutations in the HNF-1α gene leading to maturity onset diabetes of the young type 3.Semantic proximity Read ↗

Mody-3: novel HNF1A mutation and the utility of glucagon-like peptide (GLP)-1 receptor agonist therapy.Semantic proximity Read ↗

Co-inheritance of HNF1a and GCK mutations in a family with maturity-onset diabetes of the young (MODY): implications for genetic testing.Semantic proximity Read ↗

Case Report: Beyond type 1 diabetes: a case of delayed MODY1 diagnosis and successful transition to sulfonylurea therapySemantic proximity Read ↗

[A Dutch family with an autosomal dominant form of diabetes mellitus as a result of a mutation in the HNF1 alpha-gene (MODY3)].Semantic proximity Read ↗

Mutations in GCK and HNF-1alpha explain the majority of cases with clinical diagnosis of MODY in Spain.Semantic proximity Read ↗

The spectrum of HNF1A gene mutations in Greek patients with MODY3: relative frequency and identification of seven novel germline mutations.Semantic proximity Read ↗

Clinical characteristics and diagnostic criteria of maturity-onset diabetes of the young (MODY) due to molecular anomalies of the HNF1A gene.Semantic proximity Read ↗

An Italian MODY family with proband and son carrying variants in GCK and HFN1A: is it a true case of digenic MODY?Semantic proximity Read ↗

Triple diabetes: coexistence of type 1 diabetes mellitus and a novel mutation in the gene responsible for MODY3 in an overweight adolescent.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.