Article
Network analysis of enzyme activities and metabolite levels and their relationship to biomass in a large panel of Arabidopsis accessions.
The Plant cell - 1 Aug 2010
Sulpice Ronan, Trenkamp Sandra, Steinfath Matthias, Usadel Bjorn, Gibon Yves, Witucka-Wall Hanna, Pyl Eva-Theresa, Tschoep Hendrik, Steinhauser Marie Caroline, Guenther Manuela, Hoehne Melanie, Rohwer Johann M, Altmann Thomas, Fernie Alisdair R, Stitt Mark
Abstract excerpt
Natural genetic diversity provides a powerful resource to investigate how networks respond to multiple simultaneous changes. In this work, we profile maximum catalytic activities of 37 enzymes from central metabolism and generate a matrix to investigate species-wide connectivity between metabolites, enzymes, and biomass. Most enzyme activities change in a highly coordinated manner, especially those in the...
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