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Article

Genetic and household determinants of predisposition to human hookworm infection in a Brazilian community.

The Journal of infectious diseases - 15 Sept 2010

Quinnell Rupert J, Pullan Rachel L, Breitling Lutz Ph, Geiger Stefan M, Cundill Bonnie, Correa-Oliveira Rodrigo, Brooker Simon, Bethony Jeffrey M

Abstract excerpt

BACKGROUND: Predisposition to heavy or light human hookworm infection is consistently reported in treatment-reinfection studies. A significant role for host genetics in determining hookworm infection intensity has also been shown, but the relationship between host genetics and predisposition has not been investigated. METHODS: A treatment-reinfection study was conducted among 1302 individuals in Brazil. Bivariate...

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Identifiers

PMID: 20681887
DOI: 10.1086/655813
PMCID: PMC2938471

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