Article
Biomarkers with predictive and prognostic function in non-small cell lung cancer: ready for prime time?
Journal of the National Comprehensive Cancer Network : JNCCN - 1 Jul 2010
Aggarwal Charu, Somaiah Neeta, Simon George R
Abstract excerpt
Lung cancer is the leading cause of cancer-related mortality in the United States. Non-small cell lung cancer (NSCLC) accounts for approximately 85% of all lung cancers. Most patients with NSCLC present with locoregionally advanced or metastatic disease, for which response rates and median overall survival remain poor. Platinum-based chemotherapy is the mainstay of treatment for NSCLC in both adjuvant and...
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