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Article

[Ni<sup>II</sup>(3-OMe-salophene)]: A Potent Agent with Antitumor Activity

29 Jul 2010

Abstract excerpt

In this study, we investigated the anticancer properties of methoxy-substituted nickel(II)(salophene) derivatives. We demonstrated that the most active complex [NiII(3-OMe-salophene)] is not necrotic in Burkitt-like lymphoma cells (BJAB) and human B-cell precursor cells (Nalm-6). [NiII(3-OMe-salophene)] inhibited proliferation and induced apoptosis in a concentration dependent manner, giving evidence for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20669965
DOI: 10.1021/jm100459k

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