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Article

Deletion of chromosome 21 and normal intelligence: molecular definition of the lesion.

Human genetics - 1 Jun 1991

Korenberg J R, Kalousek D K, Anneren G, Pulst S M, Hall J G, Epstein C J, Cox D R

Abstract excerpt

Application of a method for the fine structure analysis of unbalanced chromosomal rearrangements using quantitative Southern blot analysis has established that an individual of normal intelligence and largely normal appearance has a significant interstitial deletion of chromosome 21. Using high resolution cytogenetic analysis and molecular analysis with five single copy DNA sequences unique to chromosome 21 and a...

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PMID: 2066097
DOI: 10.1007/BF00204163

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SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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