Article
Phylogenetic variation of Aggregatibacter actinomycetemcomitans serotype e reveals an aberrant distinct evolutionary stable lineage.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2010
van der Reijden Wil A, Brunner Jorg, Bosch-Tijhof Carolien J, van Trappen Stefanie, Rijnsburger Martine C, de Graaff Marcel P W, van Winkelhoff Arie J, Cleenwerck Ilse, de Vos Paul
Abstract excerpt
The periodontal pathogen Aggregatibacter actinomycetemcomitans that comprises six serotypes (a-f), is often identified by PCR-based techniques targeting the 16S rRNA gene. In this study, 16S rRNA gene sequence analysis revealed an aberrant cluster of 19 strains within serotype e, denoted as serotype e'. The 16S rRNA gene sequence similarities found between serotype e' strains ranged from 99.7% to 100.0%, whereas...
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