Article
Fabrication and characterization of an inorganic gold and silica nanoparticle mediated drug delivery system for nitric oxide.
Nanotechnology - 30 Jul 2010
Das Amitava, Mukherjee Priyabrata, Singla Sumit K, Guturu Praveen, Frost Megan C, Mukhopadhyay Debabrata, Shah Vijay H, Patra Chitta Ranjan
Abstract excerpt
Nitric oxide (NO) plays an important role in inhibiting the development of hepatic fibrosis and its ensuing complication of portal hypertension by inhibiting human hepatic stellate cell (HSC) activation. Here we have developed a gold nanoparticle and silica nanoparticle mediated drug delivery system containing NO donors, which could be used for potential therapeutic application in chronic liver disease. The gold...
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