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Article

A Seven-Gene Set Associated with Chronic Hypoxia of Prognostic Importance in Hepatocellular Carcinoma

30 Jun 2010

Abstract excerpt

PURPOSE: Hepatocellular carcinomas (HCC) have an unpredictable clinical course, and molecular classification could provide better insights into prognosis and patient-directed therapy. We hypothesized that in HCC, certain microenvironmental regions exist with a characteristic gene expression related to chronic hypoxia which would induce aggressive behavior. EXPERIMENTAL DESIGN: We determined the gene expression...

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Share to Cancer, Hypoxia, and Metabolism
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PMID: 20592013
DOI: 10.1158/1078-0432.ccr-09-3274

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