Article
Copy number variation and association over T-cell receptor genes--influence of DNA source.
Immunogenetics - 1 Aug 2010
Schwienbacher Christine, De Grandi Alessandro, Fuchsberger Christian, Facheris Maurizio F, Svaldi Mirija, Wjst Matthias, Pramstaller Peter P, Hicks Andrew A
Abstract excerpt
Genomic copy number variants (CNVs) are a common, heritable source of inter-individual differences in genomic sequence. Their influence on phenotypic variability and their involvement in the pathogenesis of several common diseases is well established and the object of many current studies. In the course of examining CNV association to various quantitative traits in a general population, we have detected a strong...
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