Article
Mapping self-reports of working memory deficits to executive dysfunction in Fragile X Mental Retardation 1 (FMR1) gene premutation carriers asymptomatic for FXTAS.
Brain and cognition - 1 Aug 2010
Kogan Cary S, Cornish Kim M
Abstract excerpt
Fragile X Syndrome is a neurodevelopmental disorder that is caused by the silencing of a single gene on the X chromosome, the Fragile X Mental Retardation 1 (FMR1) gene. In recent years, the premutation ("carrier") status has received considerable attention and there is now an emerging consensus that despite intellectual functioning being within the average range premutation males present with subtle executive...
Topics
- Adolescent
- Adult
- Aged
- Ataxia
- Cognition Disorders
- Executive Function
- Fragile X Mental Retardation Protein
- Fragile X Syndrome
- Genetic Predisposition to Disease
- Heterozygote
- Humans
- Male
- Memory Disorders
- Memory, Short-Term
- Middle Aged
- Mutation
- Self-Assessment
- Tremor