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Bone Marrow Mesenchymal Stem Cells: Historical Overview and Concepts

21 Jun 2010

Abstract excerpt

This review describes the historical emergence of the concept of bone marrow mesenchymal stem cells (MSCs), summarizing data on Wolf and Trentin's hematopoietic inductive microenvironment; Dexter's hematopoiesis-supportive stromal cells; Friedenstein's osteogenic cells; and Pittenger's trilineal osteoblastic, chondrocytic, and adipocytic precursors; to finally introduce the specific bone marrow mesenchymal stem...

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PMID: 20565251
DOI: 10.1089/hum.2010.115

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