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Article

Determination of knockdown resistance allele frequencies in global human head louse populations using the serial invasive signal amplification reaction

18 Jun 2010

Abstract excerpt

BACKGROUND: Pediculosis is the most prevalent parasitic infestation of humans. Resistance to pyrethrin- and pyrethroid-based pediculicides is due to knockdown (kdr)-type point mutations in the voltage-sensitive sodium channel alpha-subunit gene. Early detection of resistance is crucial for the selection of effective management strategies. RESULTS: Kdr allele frequencies of lice from 14 countries were determined...

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PMID: 20564731
DOI: 10.1002/ps.1979

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