Article
Analysis of clinical and molecular characteristics of Wiskott-Aldrich syndrome in 24 patients from 23 unrelated Chinese families.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 May 2010
Zhang Zhi-Yong, Xiao Hui-Qin, Jiang Li-Ping, Zhou Yu, Zhao Qin, Yu Jie, Liu Wei, Yang Xi-Qiang, Zhao Xiao-Dong
Abstract excerpt
The clinical data of 24 children with Wiskott-Aldrich syndrome (WAS) from 23 unrelated Chinese families were reviewed in the present study. WAS protein (WASP) expression in peripheral blood mononuclear cells was examined by flow cytometry (FCM); WASP gene was amplified by PCR and directly sequenced to analyze mutations in the WASP gene in patients and their female relatives. FCM analysis of 21 patients showed...
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