Mutation analysis of factor VIII in Korean patients with severe hemophilia A.

Abstract excerpt

Hemophilia A is an X-linked recessive disorder caused by mutations of the factor VIII gene. The mutation spectrum has been reported in various populations, but not in Koreans. Mutation analysis of the factor VIII gene was performed in 22 unrelated Korean patients with severe hemophilia A. We extracted genomic DNA from their blood, and assessed intron inversions, deletions, and point mutations by direct DNA...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Asian People
• Share to DNA Mutational Analysis
• Share to Factor VIII