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Article

Multiple nucleotide substitutions in the Neisseria meningitidis serogroup C ctrA gene cause false-negative detection by real-time PCR.

Journal of clinical microbiology - 1 Aug 2010

Cavrini Francesca, Liguori Giovanna, Andreoli Arianna, Sambri Vittorio

Abstract excerpt

Two strains of Neisseria meningitidis serogroup C with disparate sequences of ctrA were isolated. The nucleotide substitutions did not alter the corresponding protein sequences, but they impeded the detection of these meningococcal isolates by real-time PCR.

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Identifiers

PMID: 20519469
DOI: 10.1128/JCM.00103-10
PMCID: PMC2916631

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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