Article
The rate of MEFV gene mutations in hematolymphoid neoplasms.
International journal of immunogenetics - 1 Oct 2010
Celik S, Erikci A A, Tunca Y, Sayan O, Terekeci H M, Umur E E, Torun D, Tangi F, Top C, Oktenli C
Abstract excerpt
The aim of this study was to determine the rate of MEFV gene mutations, the gene responsible for familial Mediterranean fever (FMF), in patients with hematolymphoid neoplasm. The rate of the five most common MEFV gene mutations (M694V, M680I, V726A, M694I and E148Q) was determined in 46 patients with hematolymphoid neoplasm. We found a high frequency of carriers in patients with multiple myeloma (60%) and acute...
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