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Article

New mutation versus exclusion at the alpha-1-antitrypsin locus: a multifaceted approach in a problematical paternity case.

Human heredity - 1 Jan 1991

Bender K, Kasulke D, Mayerovà A, Hummel K, Weidinger S, Epplen J T, Wienker T F

Abstract excerpt

In a case of disputed paternity with overwhelming indications of fatherhood for the putative father, as supported by serological tests and biostatistical evaluation, a classical exclusion constellation was found at the alpha 1-antitrypsin (PI) locus: mother PI M1; child PI M1M3, and putative father PI M1M2. Additional studies included PI oligonucleotide phenotyping and DNA fingerprint analysis. Results from the...

Topics

Adult
Alleles
Base Sequence
Child, Preschool
DNA Fingerprinting
Female
Genetic Markers
Humans
Male
Mutation
Paternity
Probability

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

alpha 1-Antitrypsin

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Identifiers

PMID: 2050377
DOI: 10.1159/000153966

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2050377-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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