Th17 cells and regulatory T cells: new light on pathophysiology of preeclampsia

Abstract excerpt

Preeclampsia (PE) occurs in 3–5% of pregnancies and is a major cause of maternal, fetal and neonatal mortality. Although a multitude of immune and vascular defects have been proposed to explain the etiology of this disease, it is generally accepted that defective control of effector T cells by regulatory T (Treg) cell leads to fetal rejection, causing maternal hypertension and the associated clinical...

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