Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High prevalence of fulminant hepatic failure among patients with mutant alleles for truncation of ATP7B in Wilson's disease.

Scandinavian journal of gastroenterology - 1 Oct 2010

Okada Toshihide, Shiono Yuta, Kaneko Yoshibumi, Miwa Kazuhiro, Hasatani Kenkei, Hayashi Yoshiaki, Mibayashi Hiroshi, Aoyagi Hiroyuki, Tsuji Shigetsugu, Yoshimitsu Masashi, Hayashi Hisao, Yamagishi Masakazu

Abstract excerpt

OBJECTIVE: Although many mutations of the Wilson's disease (WD) gene (ATP7B) have been reported, few data exist regarding the occurrence of fulminant hepatic failure (FHF). We sought to determine if genotypic assignment according to type of protein-product could be related to the prevalence of FHF among patients with WD. MATERIAL AND METHODS: We performed gene analysis in Japanese patients with WD as well as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to Cation Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Codon, Nonsense

Share to Copper-Transporting ATPases

Share to Hepatolenticular Degeneration

Share to Liver Failure, Acute

Share to Mutagenesis, Insertional

Share to Sequence Deletion

Source

Identifiers

PMID: 20491539
DOI: 10.3109/00365521.2010.492527

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High prevalence of fulminant hepatic failure among patients with mutant alleles for truncation of ATP7B in Wilson's disease.PMID 20491539Read ↗

Clinical characteristics and genetic features of patients with Wilson's disease in southwestern China.Semantic proximity Read ↗

Prevalence of Wilson disease based on genome databases in Japan.Semantic proximity Read ↗

Genetic studies discover novel coding and non-coding mutations in patients with Wilson's disease in China.Semantic proximity Read ↗

[Analysis of clinical phenotypes and ATP7B gene variants in 75 children patients with Wilson' s disease].Semantic proximity Read ↗

Mutational analysis of ATP7B in north Chinese patients with Wilson disease.Semantic proximity Read ↗

Mutational characterization of ATP7B gene in 103 Wilson's disease patients from Southern China: identification of three novel mutations.Semantic proximity Read ↗

Distinct clinical courses according to presenting phenotypes and their correlations to ATP7B mutations in a large Wilson's disease cohort.Semantic proximity Read ↗

[A study of Wilson's disease gene encoded products and gene mutations].Semantic proximity Read ↗

Mutations of ATP7B gene in Wilson disease in Japan: identification of nine mutations and lack of clear founder effect in a Japanese population.Semantic proximity Read ↗

Wilson disease in the South chinese han population.Semantic proximity Read ↗

ATP7B Genotype and Chronic Liver Disease Treatment Outcomes in Wilson Disease: Worse Survival With Loss-of-Function Variants.Semantic proximity Read ↗

Homozygous mutations in the conserved ATP hinge region of the Wilson disease gene: association with liver disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.