Article
Monocyte chemoattractant protein-1 (MCP-1) gene polymorphism as a potential risk factor for diabetic retinopathy in Japanese patients with type 2 diabetes.
Diabetes research and clinical practice - 1 Jul 2010
Katakami Naoto, Matsuhisa Munehide, Kaneto Hideaki, Matsuoka Taka-aki, Imamura Kenichi, Ishibashi Fukashi, Kanda Tsutomu, Kawai Koichi, Osonoi Takeshi, Kashiwagi Atsunori, Kawamori Ryuzo, Shimomura Iichiro, Yamasaki Yoshimitsu
Abstract excerpt
We examined the association between diabetic retinopathy and monocyte chemoattractant protein (MCP)-1 A-2518G polymorphism in 3802 Japanese type 2 diabetic subjects. The prevalence of diabetic retinopathy was higher as the number of G alleles increased, suggesting that the G allele of this polymorphism is a susceptibility allele for diabetic retinopathy.
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