A case-control association study of serotonin 1A receptor gene and tryptophan hydroxylase 2 gene in attention deficit hyperactivity disorder.

doi:10.1016/j.pnpbp.2010.05.006

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Article

A case-control association study of serotonin 1A receptor gene and tryptophan hydroxylase 2 gene in attention deficit hyperactivity disorder.

Progress in neuro-psychopharmacology & biological psychiatry - 16 Aug 2010

Shim Se-Hoon, Hwangbo Young, Kwon Young-Joon, Jeong Hee-Yeon, Lee Bun-Hee, Hwang Jung-A, Kim Yong-Ku

Abstract excerpt

Serotonergic system-related genes are likely to be involved in mechanisms underlying attention deficit hyperactivity disorder (ADHD). We investigated the association of serotonin the 1A receptor C-1019G single nucleotide polymorphism (HTR1A C-1019G SNP) and tryptophan hydroxylase 2 gene -703G/T (TPH2 -703G/T) SNP with ADHD. All of the ADHD subjects completed a comprehensive and standardized diagnostic and...

Topics

Adolescent
Alleles
Asian People
Attention Deficit Disorder with Hyperactivity
Case-Control Studies
Chi-Square Distribution
Child
Child, Preschool
Female
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Humans

Male

Neuropsychological Tests

Odds Ratio

Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 20470849
DOI: 10.1016/j.pnpbp.2010.05.006

Genes

TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.