Article
Mitochondrial dysfunction in autism spectrum disorders: cause or effect?
Biochimica et biophysica acta - 1 Jan 2000
Palmieri Luigi, Persico Antonio M
Abstract excerpt
Autism Spectrum Disorders encompass severe developmental disorders characterized by variable degrees of impairment in language, communication and social skills, as well as by repetitive and stereotypic patterns of behaviour. Substantial percentages of autistic patients display peripheral markers of mitochondrial energy metabolism dysfunction, such as (a) elevated lactate, pyruvate, and alanine levels in blood,...
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