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Article

Cortical propagation of Creutzfeldt-Jakob disease with codon 180 mutation.

Clinical neurology and neurosurgery - 1 Jul 2010

Kobayashi Shunsuke, Saito Yuko, Maki Toshiyuki, Murayama Shigeo

Abstract excerpt

A patient with Creutzfeldt-Jakob disease (CJD) with prion protein (PrP) gene codon 180 mutation (CJD 180) experienced cognitive decline over the 1.5-year period before her death. Serial magnetic resonance imaging (MRI) studies tracked stepwise propagation of cortical abnormal swelling and T2 elongations. On postmortem examination, the cortical areas affected by CJD for relatively short periods were associated...

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Identifiers

PMID: 20409635
DOI: 10.1016/j.clineuro.2010.03.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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