Article
Polymorphisms in the gene encoding bovine interleukin-10 receptor alpha are associated with Mycobacterium avium ssp. paratuberculosis infection status.
BMC genetics - 15 Apr 2010
Verschoor Chris P, Pant Sameer D, You Qiumei, Schenkel Flavio S, Kelton David F, Karrow Niel A
Abstract excerpt
BACKGROUND: Johne's disease is a chronic inflammatory bowel disease (IBD) of ruminants caused by Mycobacterium avium ssp. paratuberculosis (MAP). Since this pathogen has been implicated in the pathogenesis of human IBDs, the goal of this study was to assess whether single nucleotide polymorphism (SNPs) in several well-known candidate genes for human IBD are associated with susceptibility to MAP infection in dairy...
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