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Leucocytes and intrinsic ROS production may be factors compromising sperm chromatin condensation status

17 Mar 2010

Abstract excerpt

Considering that the final protection of the DNA against major assaults in terms of chromatin condensation is finalized in the epididymis, it is not known how sperm production of reactive oxygen species (ROS) and inflammatory processes can contribute to protamine deficiency that is predetermined in the testes. Therefore, this study aimed at investigating relationships between poor chromatin condensation,...

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PMID: 20384795
DOI: 10.1111/j.1439-0272.2009.00967.x

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