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Changes in fetal prevalence and outcome for trisomies 13 and 18: a population-based study over 23 years

12 Apr 2010

Abstract excerpt

OBJECTIVE: Changes in prenatal diagnosis and maternal age are likely to have an impact on live born prevalence of trisomies 13 and 18. We investigated trends in diagnosis, prevalence, and survival in these conditions. METHODS: A population-based study of one UK health region in 1985-2007 using a well-established congenital abnormality register. Individual records were reviewed and live birth and maternal age data...

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PMID: 20384468
DOI: 10.3109/14767051003758879

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