Article
Two nonrecombining sympatric forms of the human malaria parasite Plasmodium ovale occur globally.
The Journal of infectious diseases - 15 May 2010
Sutherland Colin J, Tanomsing Naowarat, Nolder Debbie, Oguike Mary, Jennison Charlie, Pukrittayakamee Sasithon, Dolecek Christiane, Hien Tran Tinh, do Rosário Virgilio E, Arez Ana Paula, Pinto João, Michon Pascal, Escalante Ananias A, Nosten Francois, Burke Martina, Lee Rogan, Blaze Marie, Otto Thomas Dan, Barnwell John W, Pain Arnab, Williams John, White Nicholas J, Day Nicholas P J, Snounou Georges, Lockhart Peter J, Chiodini Peter L, Imwong Mallika, Polley Spencer D
Abstract excerpt
BACKGROUND: Malaria in humans is caused by apicomplexan parasites belonging to 5 species of the genus Plasmodium. Infections with Plasmodium ovale are widely distributed but rarely investigated, and the resulting burden of disease is not known. Dimorphism in defined genes has led to P. ovale parasites being divided into classic and variant types. We hypothesized that these dimorphs represent distinct parasite...
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