Portrait of an oocyte: our obscure origin

Abstract excerpt

Oocytes play a pivotal role in the cycle of human life. As we discuss here, after emerging from germline stem cells in the fetus, they grow in a follicular niche in which development is harmonized for timely ovulation and hormone secretion after puberty. Most human oocytes have poor developmental competence and are peculiarly vulnerable to chromosomal malsegregation, especially as women pass the optimal years of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Prenatal Screening and Diagnostics
• Share to Renal and related cancers
• Share to Reproductive Biology and Fertility