Article
Genetic diversity in Campylobacter jejuni is associated with differential colonization of broiler chickens and C57BL/6J IL10-deficient mice.
Microbiology (Reading, England) - 1 Jul 2010
Wilson David L, Rathinam Vijay A K, Qi Weihong, Wick Lukas M, Landgraf Jeff, Bell Julia A, Plovanich-Jones Anne, Parrish Jodi, Finley Russell L, Mansfield Linda S, Linz John E
Abstract excerpt
Previous studies have demonstrated that Campylobacter jejuni, the leading causative agent of bacterial food-borne disease in the USA, exhibits high-frequency genetic variation that is associated with changes in cell-surface antigens and ability to colonize chickens. To expand our understanding of the role of genetic diversity in the disease process, we analysed the ability of three C. jejuni human disease...
Topics
- Animals
- Bacterial Proteins
- Campylobacter Infections
- Campylobacter jejuni
- Chickens
- Disease Reservoirs
- Genetic Variation
- Humans
- Interleukin-10
- Mice
- Mice, Inbred C57BL
- Mice, Knockout