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Article

Comparison of rifabutin susceptibility and rpoB mutations in multi-drug-resistant Mycobacterium tuberculosis strains by DNA sequencing and the line probe assay.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Oct 2010

Yoshida Shiomi, Suzuki Katsuhiro, Iwamoto Tomotada, Tsuyuguchi Kazunari, Tomita Motohisa, Okada Masaji, Sakatani Mitsunori

Abstract excerpt

We compared rifabutin susceptibility and rpoB mutations in 98 multi-drug-resistant strains of Mycobacterium tuberculosis (MDR-TB) by DNA sequencing and with a line probe assay using the commercially available INNO-LiPA Rif. TB kit (the LiPA). Our results indicated that rifabutin continues to remain active against MDR-TB strains harboring certain genetic alterations and also that the LiPA might be useful in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20354890
DOI: 10.1007/s10156-010-0057-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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