Article
Viral hepatocarcinogenesis.
Oncogene - 22 Apr 2010
Tsai W-L, Chung R T
Abstract excerpt
Hepatocellular carcinoma (HCC) is the fifth most common cancer and the third leading cause of cancer death worldwide. Despite recent advances in the diagnosis and treatment of HCC, its prognosis remains dismal. Infection with hepatitis B virus (HBV) and hepatitis C virus (HCV) are the major risk factors for HCC. Although both are hepatotropic viral infections, there are important differences between the oncogenic...
Topics
- Animals
- Fatty Liver
- Hepatitis B
- Hepatitis B virus
- Hepatitis C
- Humans
- Liver Cirrhosis
- Liver Neoplasms
- Mutation
- Oxidative Stress
- Trans-Activators
- Viral Load
- Viral Regulatory and Accessory Proteins