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Inheritance of DNA Transferred from American Trypanosomes to Human Hosts

11 Feb 2010

Abstract excerpt

Interspecies DNA transfer is a major biological process leading to the accumulation of mutations inherited by sexual reproduction among eukaryotes. Lateral DNA transfer events and their inheritance has been challenging to document. In this study we modified a thermal asymmetric interlaced PCR by using additional targeted primers, along with Southern blots, fluorescence techniques, and bioinformatics, to identify...

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PMID: 20169193
DOI: 10.1371/journal.pone.0009181

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