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Article

Autoimmune chronic active hepatitis in a family.

Gut - 1 Mar 1991

Hodges S, Lobo-Yeo A, Donaldson P, Tanner M S, Vergani D

Abstract excerpt

A positive family history of autoimmune disease is common among patients with autoimmune chronic active hepatitis, but usually autoimmunity is directed at organs other than the liver. We document for the first time the multiple occurrence of autoimmune chronic active hepatitis in a family. Out of a sibship of seven, three sisters developed this, one sister developed coeliac and autoimmune thyroid disease, one...

Topics

Adolescent
Autoimmune Diseases
Celiac Disease
Child
Copper
Female
Genetic Predisposition to Disease
HLA-DR Antigens
HLA-DR3 Antigen
Hepatitis, Chronic
Humans
Immunoglobulin G

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Pedigree

T-Lymphocytes

Thyroid Diseases

Source

Open in PubMed Open full text

Identifiers

PMID: 2013424
DOI: 10.1136/gut.32.3.299
PMCID: PMC1378838

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2013424-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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